Lot Data · Per Lot

Numbers verify the chemistry.

Every Cupratec lot ships with a UV-Vis spectrum, a measured Cu²⁺ : peptide molar ratio, 6-month solution-stability data, and a color ΔE against the in-house master lot. The lot report is how the atelier proves coordination — not assumes it.

Cupratec lot-release bench — blue lyophilized copper-peptide vials photographed under the inspection lamp; every vial label corresponds to a lot-specific UV-Vis spectrum and Cu²⁺ : peptide ratio report.

Cupratec lot-release bench — copper-peptide vials photographed under the inspection lamp, every label corresponding to a lot-specific UV-Vis spectrum and Cu²⁺ : peptide ratio report.

Lot-release bench · captured during a production day

Lot Data, on Every Lot

The numbers verify the chemistry.

A GHK-Cu lot without a UV-Vis spectrum is just a blue powder. Every Cupratec lot ships with the characterisation data formulators actually need — and the analytical packet behind it on request.

≈622 nm

λmax · Cu(II) d-d band

ΔE < 1.0

Color vs. master lot

6-month

Solution stability data

UV-Vis spectrum on every lot — λmax position and absorbance at brand-relevant wavelengths, the diagnostic for intact Cu(II) coordination.

Cu²⁺ : peptide molar ratio by ICP-MS or atomic absorption, target with documented tolerance — never assumed from synthesis stoichiometry.

Solution stability + color ΔE, tracked through 6 months at 25 / 40 / 60 °C against an in-house master-lot reference.

View a sample lot report (PDF)Inside the lot-data programme

Cu²⁺ Characterisation · On Every Lot

What every Cupratec lot is tested for.

The Cu²⁺ panel runs on every lot before release — it is the test set that defines whether a copper-peptide lot is what the spec says it is. The four lines below are documented on the lot release report and available as raw analytics under mutual NDA.

Test	Method	Target	Why we run it
Cu²⁺ : peptide molar ratio	ICP-MS (Cu) + HPLC-UV (peptide) with internal standard	1.00 ± 0.05 (theoretical 1:1)	The single most important Cu-peptide spec — bioactivity scales with the bound fraction, not the total peptide. Out-of-band lots are held.
UV-Vis · Cu(II) d-d band	200–800 nm scan in chelator-free pure water	λmax 620 ± 5 nm · broad single band	Direct visual + spectral confirmation of intact tetraamine coordination. Shifted or split λmax flags a coordination problem.
Solution stability (6 months)	25 / 40 / 60 °C across reference and finished-product matrices	Documented decay envelope; release-spec retention ≥ 90% at 6 mo / 25 °C	Lets formulators size shelf-life claims for the active independently of the carrier system; basis for finished-product stability scoping.
Color ΔE vs. master lot	CIELab against in-house Cupratec master reference	ΔE < 1.0 (visually indistinguishable)	Catches subtle copper-loading or impurity-profile drift the molar-ratio measurement can absorb but the human eye in a finished product will not.

Peptide-Level Analytics

The synthesis side of the chemistry.

Before the copper is coordinated, the peptide has to be a characterised peptide. These are the analytical lines Cupratec runs on the peptide itself — alongside the Cu²⁺ panel above, never as a substitute for it.

Test	Method	Target	Why we run it
HPLC purity (peptide)	RP-HPLC at the peptide's UV-active wavelength	≥ 99.0%	Standard purity floor for cosmetic-grade actives. Released lots do not contain peptide-impurity peaks above the integration threshold.
Identity by mass spec	ESI-MS, observed vs. theoretical [M+H]⁺	Confirmed (±0.5 Da)	Sequence confirmation; rules out the synthesis-side failure modes that can hide behind HPLC purity (e.g. truncations at the same retention time).
Water content (Karl Fischer)	Coulometric KF	≤ 8.0% (lyophilised powder)	Lyophilisation control. Out-of-band water increases the dissociation kinetics of the Cu(II)-peptide complex during long-term storage.
Residual solvents	GC headspace	ICH Q3C limits	Synthesis solvent residues; relevant for any peptide active going into a leave-on cosmetic.

Mesotherapy-Grade Lots

For licensed clinical use, only.

Cupratec ships a mesotherapy-grade lot variant of select Cu-peptides for licensed mesotherapy and aesthetic-clinic buyers. These lots add bacterial-endotoxin and microbial- limits testing on top of the standard Cu²⁺ + peptide analytical packet — and ship only on clinic-licence verification.

Cosmetic-grade default lots do not carry these tests; see the B2B policy for how the qualification works.

Test	Method	Target	Why we run it
Bacterial endotoxin	LAL (gel-clot / kinetic chromogenic)	< 0.25 EU/mg	Required for any lot intended for licensed clinical mesotherapy use. Cosmetic-only lots do not carry this test by default.
Microbial limits	USP <61>/<62>	Compliant	Sterile-route-adjacent applications. Same scoping as above — mesotherapy lots only, on clinic-licence verification.

Lot Report Contents

What lands on your QA bench.

Every commercial lot ships with the release report below. On request we attach the raw analytics — UV-Vis trace, HPLC chromatogram with peak integration, mass spectrum, stability series, and the master-lot ΔE photograph — as the QA work-packet your dossier needs.

Cu²⁺ : peptide ratio

Measured value with documented tolerance, ICP-MS / AA traceable.

UV-Vis spectrum

λmax, absorbance at brand-relevant wavelengths, full 200–800 nm trace on request.

Solution-stability series

Decay envelope across 25 / 40 / 60 °C, 6-month timepoints.

Color ΔE

CIELab value against the in-house master lot; photograph available on request.

HPLC purity + identity

Peak-integration chromatogram and ESI-MS confirmation of the peptide molecule.

Lot release statement

Single-page commercial release document signed by QA; the version your buyer-side dossier files.

From the Atelier

Sample a Cupratec lot.

First response under 12 hours. We send a 25 g sample of the active you specify, the lot's UV-Vis spectrum, the Cu²⁺ : peptide ratio measurement, and a feasibility note for the formulation application you have in mind.