The Craft
How we prepare and characterise copper peptides.
Copper-peptide coordination can change with the surrounding formulation, including its pH and chelators. We prepare the active and define its batch analysis against the agreed written specifications, giving formulation teams a starting point for trials.
01 · Method
Copper loading, purification, and drying.
Our process controls copper loading, purification, and drying to preserve the complex. Batch analysis is defined by the agreed written specifications.
- Solid-phase peptide synthesis on cosmetic-grade resins
- Cu²⁺ titration under controlled pH to defined molar ratio
- Purification with Cu-aware buffers (no chelators in line)
- Lyophilisation with stability-tracked excipients
02 · Characterisation
Define the evidence for the lot.
Ask sales for the matching batch COA. If the project requires UV-Vis, a Cu²⁺ : peptide ratio, solution-stability work, or colour ΔE, agree the method, specification, availability, timing, and cost before quotation; those items are not implied for every lot.
- UV-Vis spectrum (λmax + ε at brand-relevant wavelengths)
- Cu²⁺ : peptide molar ratio (target ± documented tolerance)
- Solution-stability conditions and duration agreed for the project
- Colour ΔE against an in-house master lot
03 · Custom
Custom Cu-peptide work, gram scale up.
Contact us about custom copper-peptide synthesis, including biotinylated GHK-Cu, palmitoyl variants, AHK-Cu / GHK-Cu blends, and Cu-Glutathione. Pilot work starts at 25 g, with lead times of 30–60 days from specification confirmation to the first lot.
- Lock the spec: peptide sequence, Cu ratio, finished form
- Pilot synthesis at 25 g; characterisation review
- Stability study scoped to your application matrix
- Scale-up at 100 g / 500 g / 1 kg increments
Working on a custom copper peptide?
Send us the target sequence, ratio, and finished form. We respond with a feasibility note, a pilot-lot timeline, and a sampling protocol scoped to your brand programme.